Description

5-Chloro-1H-1,2,4-Triazole-3-Carboxylic Acid is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, combining a reactive triazole core with a carboxylic acid group, enabling its use as a key intermediate for constructing more complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing triazole motifs, which are common in antifungal, antiviral, and anticancer agents.
• Agrochemical Synthesis: Used in the research and production of modern pesticides, herbicides, and fungicides, where the triazole ring contributes to biological activity and stability.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-organic frameworks (MOFs) and catalysts due to its nitrogen-rich heterocyclic structure.
• Polymer Chemistry: Acts as a monomer or functionalizing agent for producing polymers with specific thermal or chemical resistance properties.
• Peptide Mimetics and Bioconjugation: The carboxylic acid group allows for coupling reactions, making it useful in designing peptide analogs or for bioconjugation techniques in chemical biology.
• Material Science Research: Investigated for the development of energetic materials, corrosion inhibitors, and advanced organic electronic materials.

Basic Information

Product Name	5-Chloro-1H-1,2,4-Triazole-3-Carboxylic Acid
CAS No.	21733-03-9
Molecular Formula	C3H2ClN3O2
Molecular Weight	147.52 g/mol
Synonyms	5-Chloro-1H-1,2,4-triazole-3-carboxylic acid; 3-Carboxy-5-chloro-1,2,4-triazole; 5-Chloro-3-carboxy-1,2,4-triazole; 5-Chloro-1,2,4-triazole-3-carboxylic acid; 1H-1,2,4-Triazole-3-carboxylic acid, 5-chloro-; 21733-03-9; 5-Chloro-1H-1,2,4-triazol-3-yl carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-1H-1,2,4-Triazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.