Description

Cyclohexene, 1-[2-(Triethylsilyl)Ethynyl]- (CAS 21692-54-6) is a specialized organosilicon building block featuring a cyclohexene ring and a protected terminal alkyne group. This compound is valued for its role as a key synthetic intermediate in advanced organic and medicinal chemistry, enabling the construction of complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in creating complex carbon frameworks.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The triethylsilyl-protected ethynyl group is a versatile handle for Sonogashira and other palladium-catalyzed coupling reactions.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex natural products and novel organic molecules.
• Chemical Biology Probes: Used in the synthesis of tagged molecules and probes for studying biological systems and mechanisms.

Basic Information

Product Name	Cyclohexene, 1-[2-(Triethylsilyl)Ethynyl]-
CAS No.	21692-54-6
Molecular Formula	C₁₄H₂₄Si
Molecular Weight	220.43 g/mol
Synonyms	1-[(Triethylsilyl)ethynyl]cyclohexene; 1-(2-Triethylsilylethynyl)cyclohexene; (1-Cyclohexen-1-yl)ethynyltriethylsilane; Triethyl((1-cyclohexen-1-yl)ethynyl)silane; 1-Ethynyl-1-cyclohexene triethylsilyl ether; TES-protected 1-ethynylcyclohexene; Cyclohexenyltriethylsilylacetylene
EINECS	Contact for details

Quality Control

Our production of Cyclohexene, 1-[2-(Triethylsilyl)Ethynyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.