Description

Methyl 2-Hydroxy-3-Methylbutanoate is a versatile chiral ester valued for its role as a key flavor and fragrance intermediate and a valuable building block in organic synthesis. This compound is essential for creating specific organoleptic profiles and for the production of fine chemicals and active pharmaceutical ingredients (APIs). It is primarily sought after by manufacturers in the flavor & fragrance, pharmaceutical, and agrochemical industries.

Application

• Flavor & Fragrance Industry: Used as a key intermediate in the synthesis of fruity, creamy, and buttery flavor compounds and aroma chemicals.
• Pharmaceutical Synthesis: Serves as a chiral building block for the production of active pharmaceutical ingredients (APIs) and other fine chemicals.
• Agrochemicals: Employed in the synthesis of certain pesticides and herbicides where its specific stereochemistry is required.
• Organic Synthesis: Acts as a versatile reagent for esterification and transesterification reactions, useful in academic and industrial R&D.
• Food Additive Production: Utilized in the manufacturing of certain food-grade flavoring agents.
• Cosmetics: Incorporated as a fragrance component or an intermediate in the synthesis of specialty cosmetic ingredients.

Basic Information

Product Name	Methyl 2-Hydroxy-3-Methylbutanoate
CAS No.	21632-23-5
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	Methyl 2-Hydroxy-3-Methylbutyrate; Methyl 2-Hydroxyisovalerate; 2-Hydroxy-3-Methylbutyric Acid Methyl Ester; Methyl (2S)-2-Hydroxy-3-methylbutanoate; L-Valine Lactone Methyl Ester; Methyl O-Acetyl-L-lactate (related); Methyl 2-Hydroxy-3-methylbutyrate; Methyl α-Hydroxyisovalerate
EINECS	244-492-3

Quality Control

Our Methyl 2-Hydroxy-3-Methylbutanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for flavor, fragrance, and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere if opened for prolonged periods to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0% (typical for specified isomer)
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.