Description

2-Cyclopropyl-Acetamidine Hcl is a high-purity chemical building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its unique amidine functional group attached to a cyclopropyl moiety, making it a versatile precursor for constructing complex nitrogen-containing heterocycles and pharmacologically active molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides where the cyclopropyl-amidine structure confers specific biological activity.
• Chemical Research & Development: Serves as a critical reagent in academic and industrial R&D for exploring new reaction pathways and creating libraries of complex organic molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials that require precise molecular architectures.
• Ligand and Catalyst Preparation: Utilized for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and metal-organic chemistry.

Basic Information

Product Name	2-Cyclopropyl-Acetamidine Hcl
CAS No.	21572-79-2
Molecular Formula	C5H10N2•HCl
Molecular Weight	134.61 g/mol (Free base); 171.06 g/mol (Hydrochloride salt)
Synonyms	2-Cyclopropylacetamidine Hydrochloride; Cyclopropanecetamidine Hydrochloride; (Cyclopropylmethyl)amidine Hydrochloride; 2-Cyclopropylethanimidamide Hydrochloride; Acetamidine, 2-cyclopropyl-, hydrochloride; 2-Cyclopropyl-1-iminoethylamine Hydrochloride; N-Cyclopropylmethylformamidine Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-Acetamidine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and identity confirmation. Our quality commitment aligns with cGMP principles where applicable, ensuring the material is suitable for demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and under anhydrous conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.