Description

n-[[(Diethoxyphosphinyl)Thio]Acetyl]-β-Alanine Ethyl Ester is a specialized organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its unique structure, featuring both phosphorothioate and β-alanine ester functionalities, makes it a valuable building block for creating complex molecules with targeted biological or material properties. This high-purity intermediate is essential for research and development laboratories, as well as production facilities, in the agrochemical and pharmaceutical sectors seeking to develop novel active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel insecticides and acaricides, particularly those targeting the nervous system of pests.
• Pharmaceutical Research: Used as a building block in medicinal chemistry for the development of prodrugs or enzyme inhibitors, leveraging its phosphorothioate group.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function, especially phosphatases and related proteins.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis or metal chelation studies.
• Peptide Mimetic Development: The β-alanine ethyl ester moiety allows for its incorporation into peptide analogs to modify stability and bioavailability.

Basic Information

Product Name	n-[[(Diethoxyphosphinyl)Thio]Acetyl]-β-Alanine Ethyl Ester
CAS No.	21472-77-5
Molecular Formula	C11H22NO6PS
Molecular Weight	327.33 g/mol
Synonyms	Ethyl 3-[[(diethoxyphosphinothioyl)acetyl]amino]propanoate; β-Alanine, N-[[(diethoxyphosphinyl)thio]acetyl]-, ethyl ester; Acetamide, N-(3-ethoxy-3-oxopropyl)-2-(diethoxyphosphinothioyl)-; NSC 163063; Phosphorothioic acid, [[(3-ethoxy-3-oxopropyl)amino]oxoacetyl]-, diethyl ester; Diethyl [[(3-ethoxy-3-oxopropyl)carbamoyl]thio]phosphonate
EINECS	Contact for details

Quality Control

Our n-[[(Diethoxyphosphinyl)Thio]Acetyl]-β-Alanine Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the potential sensitivity of the organophosphorus moiety, prolonged exposure to high humidity or extreme temperatures should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.