Description

1,2,3,4-Tetramethoxybenzene is a high-purity, multi-methoxylated benzene derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for pharmaceuticals, agrochemicals, and specialty materials. This compound is essential for research and production chemists in fine chemical, pharmaceutical, and material science industries seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those with polyphenolic or methoxy-substituted aromatic cores.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators requiring specific aromatic ether functionalities.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where controlled methoxy substitution is required.
• Chemical Research & Development: A versatile reagent for methodological studies in organic chemistry, including coupling reactions and functional group transformations.
• Dye and Pigment Intermediate: Used in the synthesis of specialized colorants and photographic chemicals.

Basic Information

Product Name	1,2,3,4-Tetramethoxybenzene
CAS No.	21450-56-6
Molecular Formula	C10H14O4
Molecular Weight	198.22 g/mol
Synonyms	Benzene, 1,2,3,4-tetramethoxy-; Prehnitene tetramethyl ether; Tetramethoxybenzene; 1,2,3,4-Tetramethoxy-benzene; NSC 406914; Prehnityl tetramethyl ether; 1,2,3,4-Tetramethyl prehnitate
EINECS	244-402-5

Quality Control

Our 1,2,3,4-Tetramethoxybenzene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	97 - 101 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.