Description

(2R)-2α-Methyl-6β-Methoxytetrahydro-2H-Pyran-3β-Ol is a chiral, substituted tetrahydropyran derivative that serves as a valuable synthetic intermediate and building block in advanced organic chemistry. Its defined stereochemistry and functional groups make it a critical precursor for constructing complex molecular architectures with high enantiomeric purity. This compound is primarily sought by research and development laboratories, as well as production facilities, in the pharmaceutical and fine chemical sectors for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or with complex stereochemical requirements.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to introduce specific stereocenters into target molecules.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new drug candidates, especially where the tetrahydropyran scaffold is pharmacologically relevant.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials that require high-purity chiral intermediates.
• Academic & Industrial R&D: Serves as a standard or starting material in methodological development and process chemistry studies within academic and corporate research settings.

Basic Information

Product Name	(2R)-2α-Methyl-6β-Methoxytetrahydro-2H-Pyran-3β-Ol
CAS No.	21317-50-0
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	(2R,3R,6R)-2-Methyl-6-methoxytetrahydro-2H-pyran-3-ol; (2R,3R,6R)-2-Methyl-6-methoxy-tetrahydropyran-3-ol; 2α-Methyl-6β-methoxytetrahydro-2H-pyran-3β-ol, (2R)-; 3β-Hydroxy-2α-methyl-6β-methoxytetrahydropyran; (2R,3R,6R)-2-Methyl-6-methoxy-3-hydroxytetrahydropyran; 6-Methoxy-2-methyl-tetrahydropyran-3-ol; Chiral tetrahydropyranol derivative
EINECS	Contact for details

Quality Control

Our production of (2R)-2α-Methyl-6β-Methoxytetrahydro-2H-Pyran-3β-Ol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to minimize moisture uptake. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.