Description

3',4',5',6,7,8-Hexamethoxy-5-Hydroxyflavone is a highly substituted, polymethoxylated flavonoid derivative of significant interest in advanced research and development. This compound matters for its role as a key intermediate and reference standard in the synthesis and study of bioactive natural products and novel pharmaceutical agents. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on flavonoid chemistry, nutraceutical development, and drug discovery programs.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis of novel drug candidates, particularly those targeting inflammation, oxidative stress, and metabolic disorders.
• Natural Product & Flavonoid Chemistry: Used as a building block or model compound for studying structure-activity relationships (SAR) of polymethoxylated flavonoids and their derivatives.
• Nutraceutical & Cosmetic Ingredient Research: Investigated for potential application in high-value formulations due to the bioactivity profile associated with its specific substitution pattern.
• Analytical Reference Standard: Employed in HPLC, LC-MS, and NMR for the qualitative and quantitative analysis of complex flavonoid mixtures in plant extracts or synthetic batches.
• Biochemical & Cell-Based Assays: Utilized as a tool compound to probe biological pathways and enzyme interactions related to flavonoid metabolism and signaling.

Basic Information

Product Name	3',4',5',6,7,8-Hexamethoxy-5-Hydroxyflavone
CAS No.	21187-73-5
Molecular Formula	C21H22O9
Molecular Weight	418.40 g/mol
Synonyms	5-Hydroxy-3',4',5',6,7,8-hexamethoxyflavone; 5-Hydroxy-3',4',5',6,7,8-hexamethoxy-2-phenyl-4H-chromen-4-one; 3',4',5',6,7,8-Hexamethoxy-5-hydroxyflavone; 5-Hydroxyhexamethoxyflavone; NSC 407347; Flavone, 5-hydroxy-3',4',5',6,7,8-hexamethoxy-
EINECS	Contact for details

Quality Control

Our 3',4',5',6,7,8-Hexamethoxy-5-Hydroxyflavone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.