Description

5-Chloroquinoline-8-Sulfonyl Chloride, Hydrochloride is a high-value, multi-functional chemical intermediate crucial for advanced organic synthesis. Its reactive sulfonyl chloride and quinoline core make it an essential building block for creating complex molecules with targeted properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry research targeting various disease pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the bioactive quinoline scaffold.
• Functional Material Precursor: Serves as a starting material for creating specialized dyes, pigments, and photoactive compounds.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic systems and sulfonamide derivatives.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	5-Chloroquinoline-8-Sulfonyl Chloride, Hydrochloride
CAS No.	21121-54-0
Molecular Formula	C9H6Cl2NO2S • HCl
Molecular Weight	308.57 g/mol (Free base: 272.12 g/mol)
Synonyms	8-Chlorosulfonyl-5-chloroquinoline hydrochloride; 5-Chloro-8-quinolinesulfonyl chloride hydrochloride; Quinoline-8-sulfonyl chloride, 5-chloro-, hydrochloride; 5-Chloroquinoline-8-sulphonyl chloride hydrochloride; 21121-54-0; 5-Chloro-8-quinolinesulfonyl Chloride HCl
EINECS	Contact for details

Quality Control

Our 5-Chloroquinoline-8-Sulfonyl Chloride, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.