Description

cis-8,11,14-Eicosatrienoic Acid Methyl Ester is a high-purity methyl ester derivative of the polyunsaturated fatty acid, dibomo-γ-linolenic acid (DGLA). This compound serves as a critical reference standard and synthetic intermediate in biochemical and pharmaceutical research. It is essential for researchers and manufacturers in the life sciences, nutraceutical, and specialty chemical sectors who require precise, well-characterized compounds for analytical work and product development.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for the quantification and identification of fatty acid metabolites in biological samples via GC-MS or LC-MS.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of eicosanoids, prostaglandins, and other bioactive lipid mediators for drug discovery.
• Nutritional Science Studies: Employed in research investigating the metabolism and biological effects of ω-6 fatty acid derivatives.
• Analytical Chemistry: Acts as a critical internal standard or calibration compound in chromatographic methods for fatty acid analysis.
• Cosmetic & Dermatological R&D: Investigated for potential applications in formulations targeting skin barrier function and inflammatory pathways.
• Cell Culture & In Vitro Studies: Used to supplement media in studies examining the role of specific fatty acids in cellular processes and signaling.

Basic Information

Product Name	cis-8,11,14-Eicosatrienoic Acid Methyl Ester
CAS No.	21061-10-9
Molecular Formula	C₂₁H₃₆O₂
Molecular Weight	320.51 g/mol
Synonyms	Methyl cis-8,11,14-Eicosatrienoate; Methyl all-cis-8,11,14-Eicosatrienoate; Methyl Dihomo-γ-linolenate; DGLA Methyl Ester; 8Z,11Z,14Z-Eicosatrienoic Acid Methyl Ester; Mead Acid Methyl Ester (Note: Common name for the 5,8,11 isomer); 20:3 n-6 Methyl Ester (δ8,11,14); Methyl (8Z,11Z,14Z)-icosa-8,11,14-trienoate
EINECS	Contact for details

Quality Control

Every batch of cis-8,11,14-Eicosatrienoic Acid Methyl Ester is produced and controlled under a strict quality management system. We employ advanced analytical techniques including GC-FID, GC-MS, and HPLC to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow oily liquid
Identification (IR)	Conforms to structure
Identification (GC-MS)	Conforms to reference
Assay (GC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.