Description

1,4-Dioxane, 2-(Chloromethyl)- is a versatile chloromethylated derivative of 1,4-dioxane, serving as a key reactive intermediate in advanced organic synthesis. Its bifunctional structure, featuring both an ether linkage and a reactive chloromethyl group, makes it a valuable building block for constructing complex molecular architectures. This compound is particularly relevant for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to introduce functionalized dioxane moieties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring functionalized cyclic ether scaffolds.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polymers and resins with tailored properties.
• Ligand and Chelator Preparation: Utilized in the development of crown ether analogs and other complexing agents for metal ions.
• Surface Modification: Employed to introduce reactive sites onto material surfaces for further chemical grafting.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1,4-Dioxane, 2-(Chloromethyl)-
CAS No.	21048-16-8
Molecular Formula	C5H9ClO2
Molecular Weight	136.58 g/mol
Synonyms	2-(Chloromethyl)-1,4-dioxane; 1,4-Dioxane-2-methyl chloride; 2-Chloromethyl-1,4-dioxane; (Chloromethyl)-1,4-dioxane; 1,4-Dioxan-2-ylmethyl chloride; NSC 403119; 2-(Chloromethyl)dioxane
EINECS	Contact for details

Quality Control

Our 1,4-Dioxane, 2-(Chloromethyl)- is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets precise customer requirements and internal specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.