Description

(2S)-2α-Phenylchroman-4β-Ol CAS NO 20902-95-8 is a chiral, non-racemic chemical intermediate of significant interest in advanced organic synthesis. Its defined stereochemistry and unique molecular scaffold make it a valuable building block for creating complex, optically active molecules. This compound is primarily sought by research institutions and pharmaceutical developers for applications in medicinal chemistry and asymmetric catalysis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Utilized as a building block or chiral auxiliary in stereoselective reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of novel bioactive compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: Used in university and industrial research laboratories for methodological development in organic and organometallic chemistry.

Basic Information

Product Name	(2S)-2α-Phenylchroman-4β-Ol
CAS No.	20902-95-8
Molecular Formula	C₁₅H₁₄O₂
Molecular Weight	226.27 g/mol
Synonyms	(2S)-2-Phenylchroman-4-ol; (2S)-2-Phenyl-3,4-dihydro-2H-1-benzopyran-4-ol; (2S)-2-Phenyl-4-hydroxy-3,4-dihydro-2H-chromene; (S)-2-Phenyl-4-chromanol; (S)-2-Phenyl-4-hydroxy-3,4-dihydro-2H-1-benzopyran; 4β-Hydroxy-2α-phenylchroman (2S); trans-(2S,4R)-2-Phenylchroman-4-ol
EINECS	Contact for details

Quality Control

Our (2S)-2α-Phenylchroman-4β-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and mass spectrometry for structural confirmation. A Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.