Description

Swertianin (Swertiae) CAS NO 20882-75-1 is a bioactive secoiridoid glycoside primarily isolated from plants of the genus *Swertia*. This compound is valued for its significant pharmacological properties, making it a critical reference standard and active ingredient in research and development. It is essential for manufacturers and researchers in the pharmaceutical, nutraceutical, and herbal extract industries seeking high-purity botanical actives for product formulation and analytical purposes.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the quality control and quantification of Swertianin in herbal drugs and finished formulations.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key starting material or intermediate in the synthesis of more complex therapeutic agents targeting liver and metabolic disorders.
• Nutraceutical & Dietary Supplement Formulation: Incorporated into supplements for its purported hepatoprotective and anti-inflammatory benefits, derived from traditional medicinal uses of *Swertia* species.
• Biomedical & Pharmacological Research: Employed in *in vitro* and *in vivo* studies to investigate mechanisms of action, efficacy, and safety profiles related to its biological activities.
• Herbal Extract Standardization: Critical for standardizing commercial herbal extracts (e.g., from *Swertia chirayita*) to ensure consistent potency and therapeutic effect.
• Cosmeceutical Applications: Explored in premium skincare formulations for its antioxidant properties, which may help protect skin from oxidative stress.

Basic Information

Product Name	Swertianin (Swertiae)
CAS No.	20882-75-1
Molecular Formula	C16H22O10
Molecular Weight	374.34 g/mol
Synonyms	Swertianin; Swertiamarin; Swertiamarine; (1S,4aR,5S,7aS)-5-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-1-carboxylic acid methyl ester; Swertia japonica extract constituent; 6-O-β-D-Glucosylswertiamarin
EINECS	Contact for details

Quality Control

Our Swertianin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via IR and MS, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee traceability and compliance with your quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.