Description

α-(Acetylamino)-1,3-Benzodioxole-5-Propanoic Acid CAS NO 20850-40-2 is a specialized organic compound featuring a benzodioxole core linked to a propanoic acid chain with an acetylamino substituent. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological or inflammatory pathways.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Biochemical Reagent: Used in biochemical assays and as a standard for analytical method development in quality control laboratories.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct more complex heterocyclic compounds and fine chemicals.
• Reference Standard: Acts as a high-purity standard for HPLC, LC-MS, or NMR analysis in pharmaceutical and academic research settings.

Basic Information

Item	Details
Product Name	α-(Acetylamino)-1,3-Benzodioxole-5-Propanoic Acid
CAS No.	20850-40-2
Molecular Formula	C₁₂H₁₃NO₅
Molecular Weight	251.24 g/mol
Synonyms	N-[2-(1,3-Benzodioxol-5-yl)-1-carboxyethyl]acetamide; 3-(1,3-Benzodioxol-5-yl)-2-acetamidopropanoic acid; 2-Acetamido-3-(1,3-benzodioxol-5-yl)propanoic acid; α-Acetamido-3,4-(methylenedioxy)hydrocinnamic acid; 5-[1-Carboxy-2-(acetylamino)ethyl]-1,3-benzodioxole; NSC 163182
EINECS	Contact for details

Quality Control

Our α-(Acetylamino)-1,3-Benzodioxole-5-Propanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.