Description

trans-3-Methylcyclobutanamine is a specialized chiral amine building block featuring a strained cyclobutane ring system. This compound matters for its role as a key intermediate in the synthesis of complex pharmaceutical molecules and advanced materials, where its unique three-dimensional structure imparts specific biological activity or material properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific stereochemistry for efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and advanced organic frameworks with tailored properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Item	Details
Product Name	trans-3-Methylcyclobutanamine
CAS No.	20826-77-1
Molecular Formula	C5H11N
Molecular Weight	85.15 g/mol
Synonyms	(1R,3S)-3-Methylcyclobutanamine; (1S,3R)-3-Methylcyclobutanamine; trans-3-Methylcyclobutan-1-amine; 3-Methylcyclobutanamine (trans-); (±)-trans-3-Methylcyclobutanamine; 3-Methylcyclobutanamine, trans-; 20826-77-1; Cyclobutanamine, 3-methyl-, trans-
EINECS	Contact for details

Quality Control

Our trans-3-Methylcyclobutanamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by GC or HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, supporting regulatory filings and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the amine functionality, it should be stored separately from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.