Description

(S)-3-Hydroxy-4,4,4-Trichlorobutyric Acid β-Lactone is a high-value chiral building block and a key intermediate in organic synthesis. Its significance lies in its stereochemically defined structure, which is crucial for synthesizing enantiomerically pure compounds, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by R&D chemists and process development scientists for the production of active pharmaceutical ingredients (APIs), fine chemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides.
• Fine Chemical Production: Serves as a versatile building block for complex organic molecules in specialty chemistry.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems.
• Polymer Chemistry: Can be used as a monomer for creating specialized polymers with unique properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies and the discovery of new synthetic pathways.

Basic Information

Product Name	(S)-3-Hydroxy-4,4,4-Trichlorobutyric Acid β-Lactone
CAS No.	20710-34-3
Molecular Formula	C4H3Cl3O3
Molecular Weight	197.42 g/mol
Synonyms	(S)-4,4,4-Trichloro-3-hydroxybutanoic acid β-lactone; (S)-3-Hydroxy-4,4,4-trichlorobutyric acid lactone; (S)-Trichlorolactone; (3S)-4,4,4-Trichlorooxetan-2-one; (S)-β-Trichloromethyl-β-propiolactone; (S)-HBTB; (S)-3-Hydroxy-4,4,4-trichloro-2-oxetanone
EINECS	Contact for details

Quality Control

Our (S)-3-Hydroxy-4,4,4-Trichlorobutyric Acid β-Lactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity (by HPLC), enantiomeric excess (ee), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and reducing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.