Description

1,2,4-Triazolo[4,3-B]Pyridazin-6(5H)-One is a high-purity, fused heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its unique triazolopyridazine scaffold is of significant value for constructing novel molecular architectures with targeted biological activity. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of new active ingredients and for use in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a specialty monomer or precursor for the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme inhibition and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	1,2,4-Triazolo[4,3-B]Pyridazin-6(5H)-One
CAS No.	20552-63-0
Molecular Formula	C5H4N4O
Molecular Weight	136.11 g/mol
Synonyms	1,2,4-Triazolo[4,3-b]pyridazin-6(5H)-one; 6H-[1,2,4]Triazolo[4,3-b]pyridazin-6-one; 1,2,4-Triazolo[4,3-b]pyridazin-6-ol; 20552-63-0; Triazolopyridazinone; [1,2,4]Triazolo[4,3-b]pyridazin-6(5H)-one
EINECS	Contact for details

Quality Control

Our 1,2,4-Triazolo[4,3-B]Pyridazin-6(5H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) documenting all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.