Description

2-Nitrobenzyl p-Toluenesulfonate is a specialized organic sulfonate ester compound, serving as a valuable building block and protecting group reagent in advanced synthetic chemistry. Its core value lies in its utility as a photolabile protecting group for carboxylic acids and alcohols, enabling precise, light-triggered deprotection in multi-step syntheses. This makes it a critical material for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing light-responsive systems and complex organic molecules.

Application

• Photolabile Protecting Group: Key reagent for the protection of carboxylic acids and alcohols in peptide and oligonucleotide synthesis, allowing for selective deprotection under UV light.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) requiring light-sensitive synthetic steps.
• Agrochemical Synthesis: Serves as an intermediate in the creation of advanced crop protection agents and herbicides.
• Material Science Research: Employed in the development of photoresponsive polymers, coatings, and smart materials.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex molecular architectures.
• Chemical Biology Tool: Facilitates the study of biological processes through caged compound synthesis for controlled release of bioactive molecules.

Basic Information

Product Name	2-Nitrobenzyl p-Toluenesulfonate
CAS No.	20444-09-1
Molecular Formula	C14H13NO5S
Molecular Weight	307.32 g/mol
Synonyms	2-Nitrobenzyl Tosylate; p-Toluenesulfonic Acid 2-Nitrobenzyl Ester; 4-Methylbenzenesulfonic Acid (2-Nitrophenyl)methyl Ester; α-Toluenesulfonic Acid 2-Nitrobenzyl Ester; 2-Nitrobenzyl 4-Methylbenzenesulfonate; (2-Nitrophenyl)methyl 4-methylbenzenesulfonate; o-Nitrobenzyl Tosylate; 2-NBT
EINECS	Contact for details

Quality Control

Our 2-Nitrobenzyl p-Toluenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.