Description

2-Cyclopropen-1-One, 2-Chloro-3-Phenyl- is a highly functionalized cyclopropenone derivative, serving as a versatile and reactive synthetic building block in advanced organic chemistry. Its strained three-membered ring fused with a ketone and aryl chloride substituents makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring strained ring systems or specific stereochemistry.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in [2+2] cycloadditions, ring-opening reactions, and as a dipolarophile in the construction of complex heterocycles and natural product analogs.
• Chemical Biology Probe: Useful for studying protein-ligand interactions or as a reactive handle in bioconjugation chemistry due to its unique electrophilic character.

Basic Information

Product Name	2-Cyclopropen-1-One, 2-Chloro-3-Phenyl-
CAS No.	20434-13-3
Molecular Formula	C9H5ClO
Molecular Weight	164.59 g/mol
Synonyms	2-Chloro-3-phenylcycloprop-2-en-1-one; 2-Chloro-3-phenyl-2-cyclopropen-1-one; 3-Phenyl-2-chlorocycloprop-2-enone; NSC 163044; 2-Chloro-3-phenylcyclopropenone; 2-Chloro-3-phenyl-1-cyclopropen-1-one; Phenylchlorocyclopropenone
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-phenylcyclopropenone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.