Description

2-Hydroxy-2'-Nitrobiphenyl is a specialized biphenyl derivative characterized by its distinct hydroxyl and nitro functional groups, making it a valuable intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of high-performance materials and active pharmaceutical ingredients. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop novel compounds with specific electronic or binding properties.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its biphenyl core.
• Ligand and Catalyst Precursor: Acts as a starting material for the preparation of specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Employed in the synthesis of complex organic dyes and pigments, where the nitro and hydroxyl groups contribute to color properties.
• Material Science Research: Utilized in the development of organic electronic materials, such as those for OLEDs or conductive polymers.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create more complex biaryl systems.

Basic Information

Product Name	2-Hydroxy-2'-Nitrobiphenyl
CAS No.	20281-21-4
Molecular Formula	C₁₂H₉NO₃
Molecular Weight	215.20 g/mol
Synonyms	2-(2-Nitrophenyl)phenol; 2'-Nitro[1,1'-biphenyl]-2-ol; 2-Hydroxy-2'-nitrodiphenyl; o-Hydroxy-o'-nitrobiphenyl; 2-Nitro-2'-hydroxybiphenyl; [1,1'-Biphenyl]-2-ol, 2'-nitro-; NSC 163044
EINECS	243-690-5

Quality Control

Our 2-Hydroxy-2'-Nitrobiphenyl is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and physical characteristics. Our quality commitment ensures the material is suitable for demanding applications in research and scale-up synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.