Description

2-[(Dichloroacetyl)Amino]-3-Hydroxy-3-(4-Nitrophenyl)Propyl [R-(R*,R*)]-Aminoacetate is a specialized chiral organic compound that serves as a critical synthetic intermediate or building block in advanced chemical synthesis. Its value lies in its unique molecular structure, which incorporates multiple functional groups—including a dichloroacetyl amide, a secondary alcohol, and a nitroarene—making it a versatile precursor for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of enantiomerically pure active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drug candidates, especially those targeting specific biological receptors.
• Agrochemical Research: Used in developing novel, enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for activity.
• Chemical Synthesis: Serves as a versatile precursor for introducing the 2-[(dichloroacetyl)amino] and 4-nitrophenyl motifs into more complex molecular architectures.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in research focused on developing new asymmetric synthetic methodologies.
• Bioconjugate Chemistry: Potential use in creating labeled probes or conjugates due to its reactive functional groups.
• Academic & Institutional R&D: Used in university and government laboratories for fundamental research in organic and medicinal chemistry.

Basic Information

Product Name	2-[(Dichloroacetyl)Amino]-3-Hydroxy-3-(4-Nitrophenyl)Propyl [R-(R*,R*)]-Aminoacetate
CAS No.	2980-74-7
Molecular Formula	C₁₃H₁₅Cl₂N₃O₆
Molecular Weight	380.18 g/mol
Synonyms	(2R,3R)-2-[(2,2-Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl aminoacetate; 2-[(Dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl aminoacetate (R,R-isomer); (R,R)-2-[(Dichloroacetamido)]-3-hydroxy-3-(p-nitrophenyl)propyl glycinate; Aminoacetic acid (2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl ester; 2980-74-7; (R*,R*)-2-[(Dichloroacetyl)Amino]-3-Hydroxy-3-(4-Nitrophenyl)Propyl Aminoacetate
EINECS	Contact for details

Quality Control

Every batch of 2-[(Dichloroacetyl)Amino]-3-Hydroxy-3-(4-Nitrophenyl)Propyl [R-(R*,R*)]-Aminoacetate is produced and tested under a strict quality management system. Our products undergo rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (R,R-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.