Description

Desmethylbellidifolin is a naturally occurring xanthone derivative, a class of compounds known for their diverse biological activities. This high-purity reference standard is critical for research and development in the pharmaceutical and nutraceutical sectors, where precise chemical characterization is paramount. It is primarily utilized by scientists and quality control professionals in analytical laboratories for method development, validation, and as a certified reference material.

Application

• Pharmaceutical Reference Standard: Serves as a primary standard for the identification, assay, and impurity profiling of bellidifolin and related xanthone-based drug candidates or natural extracts.
• Biochemical Research: Used as a key intermediate or probe in pharmacological studies to investigate the structure-activity relationships (SAR) of xanthones, particularly for antioxidant, anti-inflammatory, or metabolic activity.
• Natural Product Analysis: Essential for the qualitative and quantitative analysis of Gentianaceae family plants (like Swertia species) in herbal medicine quality control and standardization.
• Academic Research: Employed in university and institutional labs for synthetic chemistry, metabolic pathway studies, and as a teaching tool for advanced organic chemistry.
• Nutraceutical Development: Acts as a marker compound for the standardization of dietary supplements derived from gentian or other botanical sources containing xanthones.

Basic Information

Product Name	Desmethylbellidifolin
CAS No.	2980-32-7
Molecular Formula	C₁₃H₈O₆
Molecular Weight	260.20 g/mol
Synonyms	1,3,5,8-Tetrahydroxyxanthone; Bellidifolin; 1,3,5,8-Tetrahydroxyxanthen-9-one; 1,3,5,8-Tetrahydroxy-9H-xanthen-9-one; Demethylbellidifolin; 3,5,8-Trihydroxy-1-methoxyxanthone (common misnomer); Swertianolin aglycone (related); Xanthone derivative
EINECS	Contact for details

Quality Control

Every batch of our Desmethylbellidifolin is produced and analyzed under strict quality management protocols. We provide material characterized by advanced spectroscopic and chromatographic techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% to ≥98% by HPLC), identification data (IR, NMR, MS), and related substance analysis is supplied with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider under inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.