Description

(trans-4-Aminocyclohexyl)Acetic Acid is a versatile chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in the rigid cyclohexane backbone and functional groups, which are critical for constructing complex molecules with defined stereochemistry. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery and the synthesis of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to introduce constrained, trans-cyclohexyl amino acid motifs into peptide analogs to enhance metabolic stability and receptor selectivity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Intermediate in the development of novel herbicides and plant growth regulators with specific stereochemical requirements.
• Material Science: Potential monomer or cross-linking agent for specialty polymers requiring amine functionality and structural rigidity.
• Chemical Biology Probes: Useful for creating molecular probes and tools to study biological pathways and enzyme functions.

Basic Information

Product Name	(trans-4-Aminocyclohexyl)Acetic Acid
CAS No.	2952-00-3
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	trans-4-Aminocyclohexaneacetic Acid; (4-Aminocyclohexyl)acetic Acid (trans); 2-(trans-4-Aminocyclohexyl)acetic Acid; 4-Aminocyclohexylacetic Acid (trans); (1r,4r)-4-Aminocyclohexaneacetic Acid; (trans)-4-Aminocyclohexylacetic Acid; 4-Aminocyclohexaneacetic Acid, trans-; Cyclohexaneacetic acid, 4-amino-, trans-
EINECS	220-965-5

Quality Control

Our (trans-4-Aminocyclohexyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% trans-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.