Description

3-Bromo-2,2-Dimethylpropionic Acid is a versatile brominated organic acid building block characterized by its neopentyl-like structure, which imparts steric hindrance and influences reactivity. This compound matters as a key intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its bromine atom serves as a handle for further functionalization. It is needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in creating sterically hindered carboxylic acid derivatives and prodrugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require brominated acid components.
• Polymer & Material Science: Serves as a monomer or modifier for creating specialty polymers with unique thermal or mechanical properties.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for metal-catalyzed coupling reactions and asymmetric synthesis.
• Organic Synthesis Reagent: Acts as an alkylating agent or a precursor for generating other reactive intermediates in multi-step synthetic routes.
• Research & Development: A valuable tool for academic and industrial R&D in exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	3-Bromo-2,2-Dimethylpropionic Acid
CAS No.	2843-17-6
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	3-Bromo-2,2-dimethylpropanoic Acid; 3-Bromopivalic Acid; 2,2-Dimethyl-3-bromopropionic Acid; NSC 404058; β-Bromopivalic Acid; 3-Bromo-2,2-dimethylpropionic acid; Bromopivalic Acid; 3-Bromo-2,2-dimethylpropanoate
EINECS	220-633-2

Quality Control

Our 3-Bromo-2,2-Dimethylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product is stable at controlled room temperature for shorter periods. The container must be kept tightly sealed due to the compound's nature as a strong acid/organic solvent.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.