Description

2,2-Dichloro-N-[3-(trifluoromethyl)phenyl]acetamide is a specialized halogenated acetamide derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both dichloro and trifluoromethyl substituents, makes it a valuable building block for creating molecules with specific electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals with tailored properties.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	2,2-Dichloro-N-[3-(trifluoromethyl)phenyl]acetamide
CAS No.	2837-61-8
Molecular Formula	C9H6Cl2F3NO
Molecular Weight	272.05 g/mol
Synonyms	2,2-Dichloro-N-(3-(trifluoromethyl)phenyl)acetamide; α,α-Dichloro-3'-(trifluoromethyl)acetanilide; N-(3-Trifluoromethylphenyl)-2,2-dichloroacetamide; 2,2-Dichloroacet-3'-trifluoromethylanilide; Acetamide, 2,2-dichloro-N-[3-(trifluoromethyl)phenyl]-; 2837-61-8; 3'-(Trifluoromethyl)-α,α-dichloroacetanilide
EINECS	Contact for details

Quality Control

Every batch of 2,2-Dichloro-N-[3-(trifluoromethyl)phenyl]acetamide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.