Description

2-Chloro-N,n-Dimethylacetamide is a versatile chlorinated amide building block with significant synthetic utility. Its reactive chloroacetyl group makes it a valuable intermediate for the synthesis of pharmaceuticals, agrochemicals, and specialty fine chemicals. This compound is particularly sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical manufacturing sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing dimethylaminoethyl or related pharmacophores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile reagent for introducing the -CH2Cl group adjacent to an amide nitrogen in organic synthesis.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of certain specialty dyes and colorants.
• Polymer Modification: Can be used as a reactive monomer or cross-linking agent in specialty polymer formulations.
• Ligand and Catalyst Preparation: Useful for synthesizing complex ligands for metal catalysis.

Basic Information

Product Name	2-Chloro-N,n-Dimethylacetamide
CAS No.	2675-89-0
Molecular Formula	C4H8ClNO
Molecular Weight	121.56 g/mol
Synonyms	2-Chloro-N,N-dimethylacetamide; N,N-Dimethyl-2-chloroacetamide; Chloroacetic acid dimethylamide; 2-Chloro-N,N-dimethylacetamide; Dimethylchloroacetamide; Acetamide, 2-chloro-N,N-dimethyl-; α-Chloro-N,N-dimethylacetamide
EINECS	220-238-5

Quality Control

Our 2-Chloro-N,n-Dimethylacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by GC/HPLC, identity confirmation (IR), and impurity profiling, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, containers should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC/HPLC)	≤ 1.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.