Description

Methyl-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid CAS NO 2644-99-7 is a specialized organic synthesis intermediate featuring a tosyl-protected amino acid structure. This compound is valued for its role as a key building block in the preparation of more complex molecules, particularly in pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing peptide mimetics and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring a protected glycine derivative.
• Peptidomimetic Research: Used in medicinal chemistry to create and modify peptide-like structures for drug discovery programs targeting various diseases.
• Agrochemical Synthesis: Serves as an intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and specialty chemicals.
• Bioconjugation Chemistry: Utilized in the design of linkers and spacers for attaching functional groups to biomolecules in diagnostic and therapeutic applications.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies within university and corporate laboratories.

Basic Information

Product Name	Methyl-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid
CAS No.	2644-99-7
Molecular Formula	C10H13NO4S
Molecular Weight	243.28 g/mol
Synonyms	N-(Methylsulfonyl)-N-(p-toluenesulfonyl)glycine; (Methyl-p-toluenesulfonamido)acetic Acid; N-Methyl-N-tosylglycine; Glycine, N-methyl-N-[(4-methylphenyl)sulfonyl]-; Tosylmethylaminoacetic Acid; Methyl(tosylamino)acetic Acid; N-Methyl-N-(p-toluenesulfonyl)glycine; MTAG
EINECS	Contact for details

Quality Control

Our production of Methyl-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid adheres to stringent in-process controls and final batch testing to ensure consistent purity and performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For customers with specific purity requirements, we offer material produced under GMP-like conditions suitable for advanced research and non-GMP pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.