Description

N5-[[[(1,1-Dimethylethoxy)Carbonyl]Amino](Imino)Methyl]-N2-[(Benzyloxy)Carbonyl]-L-Ornithine is a sophisticated, protected amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a critical high-purity building block for the controlled construction of complex peptides and peptidomimetics, enabling research into novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, particularly in oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key protected precursor in the solid-phase and solution-phase synthesis of complex peptide-based drug candidates.
• Peptidomimetic Research: Used to incorporate modified ornithine residues into peptide backbones to enhance stability, bioavailability, and target specificity.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of novel enzyme inhibitors.
• Bioconjugation Chemistry: Utilized in the preparation of peptide conjugates for targeted drug delivery systems and diagnostic probes.
• Academic & Institutional Research: Employed in chemical biology and medicinal chemistry programs to study protein-protein interactions and signal transduction pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	N5-[[[(1,1-Dimethylethoxy)Carbonyl]Amino](Imino)Methyl]-N2-[(Benzyloxy)Carbonyl]-L-Ornithine
CAS No.	2601-51-6
Molecular Formula	C20H30N4O6
Molecular Weight	422.48 g/mol
Synonyms	N2-Cbz-N5-[(tert-Butoxycarbonyl)amidino]-L-ornithine; (S)-2-(((Benzyloxy)carbonyl)amino)-5-((((tert-butoxycarbonyl)amino)(imino)methyl)amino)pentanoic acid; Boc-Guanidino-Cbz-Orn-OH; Z-Orn(Boc-guanidino)-OH; Nω-Boc-Nδ-Cbz-L-Ornithine amidine; L-Ornithine, N5-[[[(1,1-dimethylethoxy)carbonyl]amino](imino)methyl]-N2-[(phenylmethoxy)carbonyl]-; CBZ-ORN(BOC-GUANIDINO)-OH
EINECS	Contact for details

Quality Control

Our N5-[[[(1,1-Dimethylethoxy)Carbonyl]Amino](Imino)Methyl]-N2-[(Benzyloxy)Carbonyl]-L-Ornithine is manufactured under strict quality systems to ensure batch-to-batch consistency for research and development. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.