Description

Cyclobutylamine is a versatile, four-membered ring aliphatic amine building block of significant importance in advanced organic synthesis. Its constrained cyclobutane structure offers unique steric and electronic properties, making it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating molecules with constrained geometries to modulate biological activity and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the cyclobutyl moiety can enhance efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral amines and ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Science: Employed as a monomer or cross-linking agent for synthesizing specialty polymers with tailored thermal and mechanical properties.
• Chemical Research: A fundamental building block in academic and industrial R&D for exploring new reaction pathways and synthesizing novel heterocyclic compounds.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of specific aroma chemicals, leveraging its amine functionality.

Basic Information

Product Name	Cyclobutylamine
CAS No.	2516-34-9
Molecular Formula	C4H9N
Molecular Weight	71.12 g/mol
Synonyms	Aminocyclobutane; Cyclobutanamine; 1-Cyclobutylamine; Cyclobutyl amine; Cyclobutaneamine; 1-Aminocyclobutane; NSC 60545
EINECS	219-746-5

Quality Control

Our Cyclobutylamine is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5%
Specific Gravity (20°C)	0.850 - 0.880
Refractive Index (n20D)	1.435 - 1.445

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.