Description

Destruxin B is a potent cyclic hexadepsipeptide mycotoxin produced by the entomopathogenic fungus *Metarhizium anisopliae*. This compound is of significant interest for its unique biological activity as a potent insecticidal and immunosuppressive agent. It serves as a critical reference standard and active research compound for scientists in the agrochemical and pharmaceutical sectors, particularly those developing novel bio-pesticides or investigating mechanisms of immune modulation.

Application

• Agrochemical Research & Development: Primary application as a reference standard and lead compound in the development of novel, environmentally friendly bio-insecticides.
• Entomological Studies: Used as a precise biochemical tool to study insect physiology, pathology, and host-pathogen interactions.
• Immunology & Pharmacology Research: Investigated for its potent immunosuppressive properties in cellular and molecular biology research.
• Mycotoxin Analysis: Serves as an essential analytical standard for the detection and quantification of destruxins in environmental and agricultural samples.
• Biochemical Pathway Elucidation: Utilized to study ion channel function and apoptosis induction in various cell lines.
• Academic & Institutional Research: A key reagent for universities and research institutes focusing on fungal metabolites and their biological impacts.

Basic Information

Product Name	Destruxin B
CAS No.	2503-26-6
Molecular Formula	C30H47N5O7
Molecular Weight	589.73 g/mol
Synonyms	Destruxin B; Cyclo[L-prolyl-L-valyl-3-hydroxy-N-methyl-L-leucyl-β-alanyl-α-hydroxy-γ-methyl-L-glutamyl]; NSC 267220; 2503-26-6; Metarhizium toxin B; DTXB; [Hydroxy(1-methyl-3-oxobutyl)amino]acetic acid cyclic derivative
EINECS	Contact for details

Quality Control

Our Destruxin B is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is thoroughly characterized using advanced analytical techniques including HPLC, MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.