Description

1,3-Dioxolan-2-One, 4-(Chloromethyl)- is a versatile chloromethylated cyclic carbonate derivative, serving as a key reactive intermediate in advanced organic synthesis. Its bifunctional nature, featuring both a reactive chloromethyl group and a cyclic carbonate moiety, makes it a valuable building block for introducing functional complexity. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries for constructing complex molecular architectures and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing heterocyclic or functionalized side chains.
• Polymer Modification: Used as a reactive monomer or cross-linking agent to introduce carbonate and chloromethyl functionalities into polymer backbones, enhancing properties like adhesion or biodegradability.
• Agrochemical Synthesis: Employed in the production of advanced herbicides, fungicides, and plant growth regulators where its reactive sites allow for tailored biological activity.
• Ligand and Catalyst Development: Serves as a scaffold for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and other catalytic processes.
• Surface Functionalization: Applied to modify material surfaces, such as silica or polymers, to introduce specific chemical handles for further conjugation or to alter surface properties.
• Specialty Chemical Production: Acts as a key intermediate for manufacturing dyes, photoinitiators, and other performance chemicals requiring its specific reactive framework.

Basic Information

Product Name	1,3-Dioxolan-2-One, 4-(Chloromethyl)-
CAS No.	2463-45-8
Molecular Formula	C4H5ClO3
Molecular Weight	136.53 g/mol
Synonyms	4-(Chloromethyl)-1,3-dioxolan-2-one; Glycerol Carbonate Chlorohydrin; Chloromethyl Ethylene Carbonate; 4-Chloromethyl-2-oxo-1,3-dioxolane; (Chloromethyl)ethylene carbonate; 2-Oxo-1,3-dioxolane-4-methyl chloride; Glycidyl Carbonate Chlorohydrin
EINECS	219-548-6

Quality Control

Our production of 1,3-Dioxolan-2-One, 4-(Chloromethyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Chloride Content	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.