Description

4-Bromo-2,6-Diisopropylphenol is a halogenated phenolic compound that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of the bromine and bulky isopropyl groups, which make it an excellent precursor for constructing complex molecular architectures through cross-coupling and functional group transformations. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring sterically hindered phenolic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the bromophenol structure is integral to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in the production of engineered polymers with specific thermal or oxidative stability properties.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and advanced resins.
• Cross-Coupling Reactions: The bromine substituent makes it a valuable substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to create biaryl structures.

Basic Information

Product Name	4-Bromo-2,6-Diisopropylphenol
CAS No.	2432-03-3
Molecular Formula	C12H17BrO
Molecular Weight	257.17 g/mol
Synonyms	2,6-Bis(1-methylethyl)-4-bromophenol; 4-Bromo-2,6-diisopropylphenol; Phenol, 4-bromo-2,6-bis(1-methylethyl)-; 4-Bromo-2,6-di-iso-propylphenol; 2,6-Diisopropyl-4-bromophenol; BDP; 4-Br-2,6-DIP
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-Diisopropylphenol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of our global customer base. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.