Description

Catalpol is a bioactive iridoid glycoside naturally found in several medicinal plants, most notably *Rehmannia glutinosa*. This compound is of significant commercial interest due to its well-documented neuroprotective, anti-inflammatory, and anti-diabetic properties, making it a valuable reference standard and a key ingredient for research and development. It is primarily sought after by manufacturers in the pharmaceutical, nutraceutical, and high-purity research chemical sectors for applications ranging from drug discovery to the formulation of standardized herbal extracts.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and standardization of herbal medicines and finished products containing *Rehmannia glutinosa*.
• Neuroprotective Agent Research: Serves as a key active ingredient in preclinical studies for neurodegenerative conditions such as Alzheimer's and Parkinson's disease.
• Anti-inflammatory Formulations: Incorporated into research for developing natural anti-inflammatory and analgesic therapeutic agents.
• Metabolic Disorder Studies: Utilized in R&D for anti-diabetic and anti-obesity drug candidates due to its effects on glucose metabolism.
• Nutraceutical & Dietary Supplements: Used as a marker compound to standardize and enhance the potency of herbal supplements targeting cognitive health and metabolic support.
• Cosmeceutical Ingredients: Applied in research for skin care products aimed at reducing inflammation and oxidative stress.

Basic Information

Product Name	Catalpol
CAS No.	2415-24-9
Molecular Formula	C15H22O10
Molecular Weight	362.33 g/mol
Synonyms	Catalposide (common misnomer, but often used interchangeably); (1S,4aS,7S,7aR)-1,4a,5,6,7,7a-Hexahydro-7-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclopenta[c]pyran-4-carbaldehyde; 6-O-β-D-Glucopyranosylcatalpol; Iridoid glycoside from Rehmannia
EINECS	219-324-6

Quality Control

Our Catalpol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via IR and MS, to ensure it meets the stringent requirements for research and industrial use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.