Description

1,2-Dichloro-3-Iodobenzene is a halogenated aromatic compound of significant interest in advanced organic synthesis. This versatile building block is valued for its unique reactivity profile, enabling the construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for use as a key intermediate in cross-coupling reactions and other functional group transformations.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing complex halogenated benzene cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the specific halogen pattern is essential for biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings due to the presence of both chlorine and iodine substituents, allowing for selective functionalization.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Organic Electronic Materials: Investigated as a building block for charge-transport materials and organic semiconductors.

Basic Information

Product Name	1,2-Dichloro-3-Iodobenzene
CAS No.	2401-21-0
Molecular Formula	C6H3Cl2I
Molecular Weight	272.90 g/mol
Synonyms	3-Iodo-1,2-dichlorobenzene; 1,2-Dichloro-3-iodo-benzene; 3-Iodo-o-dichlorobenzene; Benzene, 1,2-dichloro-3-iodo-; 2,3-Dichloroiodobenzene
EINECS	219-284-5

Quality Control

Our 1,2-Dichloro-3-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.