Description

(-)-2,3-Dimethylbutane-1,2,3-Tricarboxylic Acid CAS NO 2385-74-2 is a high-purity, chiral tricarboxylic acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a sophisticated building block and chiral auxiliary, enabling the stereoselective construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent to induce enantioselectivity in catalytic and stoichiometric reactions.
• Ligand Synthesis: Used in the preparation of chiral ligands for metal-catalyzed reactions, including hydrogenation and cross-coupling.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with specific functional and stereochemical properties.
• Agrochemical Research: A building block for developing novel chiral herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Useful in the synthesis of molecular probes and tools for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(-)-2,3-Dimethylbutane-1,2,3-Tricarboxylic Acid
CAS No.	2385-74-2
Molecular Formula	C9H14O6
Molecular Weight	218.21 g/mol
Synonyms	(-)-2,3-Dimethylbutane-1,2,3-tricarboxylic acid; (2S,3S)-2,3-Dimethylbutane-1,2,3-tricarboxylic acid; L-2,3-Dimethylbutane-1,2,3-tricarboxylic acid; (2S,3S)-2,3-Dimethyl-1,2,3-butanetricarboxylic acid; 2,3-Dimethylbutane-1,2,3-tricarboxylic acid, (-)-; 2385-74-2; Butane-1,2,3-tricarboxylic acid, 2,3-dimethyl-, (2S,3S)-
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Quality Control

Our (-)-2,3-Dimethylbutane-1,2,3-Tricarboxylic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider using a desiccant in the storage environment. Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.