Description

4-Aminomethyl-3-Nitrobenzoic Acid is a versatile aromatic compound featuring both amino and nitro functional groups on a benzoic acid backbone. This unique bifunctional structure makes it a valuable intermediate for synthesizing more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development teams in the life sciences, agrochemical, and specialty chemical industries for constructing novel compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a functionalized benzoic acid scaffold.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, pesticides, and plant growth regulators.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants due to its reactive amino and nitro groups.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polymers with specific functional properties.
• Bioconjugation and Linker Chemistry: Utilized in biochemical research for creating peptide conjugates, antibody-drug conjugates (ADCs), and diagnostic probes.
• Organic Synthesis Reagent: A versatile starting material for various organic transformations, including reduction, acylation, and cyclization reactions.

Basic Information

Product Name	4-Aminomethyl-3-Nitrobenzoic Acid
CAS No.	2372-51-2
Molecular Formula	C8H8N2O4
Molecular Weight	196.16 g/mol
Synonyms	3-Nitro-4-(aminomethyl)benzoic Acid; 4-(Aminomethyl)-3-nitrobenzoic Acid; Benzoic acid, 4-(aminomethyl)-3-nitro-; 4-Carboxy-2-nitrobenzylamine; 2-Nitro-4-carboxybenzylamine; (3-Nitro-4-carboxyphenyl)methanamine
EINECS	219-140-7

Quality Control

Our 4-Aminomethyl-3-Nitrobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.