Description

(3-Chloropropyl)Trimethylsilane is a versatile organosilicon reagent featuring both a reactive chloropropyl group and a hydrolytically stable trimethylsilyl group. This bifunctional nature makes it a critical intermediate for introducing silyl-protected alkyl chains or for serving as a linker in advanced material synthesis. It is essential for manufacturers and R&D chemists in the pharmaceutical, agrochemical, and specialty polymer industries seeking to modify surface properties or create functional hybrid materials.

Application

• Pharmaceutical Intermediates: Key building block for synthesizing active pharmaceutical ingredients (APIs) and prodrugs, often used to introduce lipophilic side chains or as a protective group strategy.
• Surface Modification & Silane Coupling Agent: Used to functionalize silica, glass, metals, and other inorganic surfaces, improving adhesion and compatibility in composite materials and coatings.
• Polymer & Resin Synthesis: Serves as a monomer or cross-linking agent in the production of silicone-modified polymers, resins, and elastomers with tailored properties.
• Agrochemical Synthesis: Intermediate in the manufacture of certain herbicides, fungicides, and plant growth regulators that benefit from silane functionality.
• Chromatography Stationary Phases: Employed to derivatize silica gel for use in HPLC columns, creating reversed-phase or specialty separation media.
• Organic Synthesis Reagent: Utilized in nucleophilic substitution reactions and as a precursor for generating organometallic reagents like Grignard or lithium compounds.

Basic Information

Product Name	(3-Chloropropyl)Trimethylsilane
CAS No.	2344-83-4
Molecular Formula	C6H15ClSi
Molecular Weight	150.72 g/mol
Synonyms	3-Chloropropyltrimethylsilane; (3-Chloropropyl)trimethylsilane; Trimethyl(3-chloropropyl)silane; γ-Chloropropyltrimethylsilane; 1-Chloro-3-(trimethylsilyl)propane; 3-(Trimethylsilyl)propyl chloride; Chloropropyltrimethylsilane; Silane, (3-chloropropyl)trimethyl-
EINECS	219-052-4

Quality Control

Our (3-Chloropropyl)Trimethylsilane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Density (20°C)	0.90 - 0.92 g/mL
Refractive Index (n20/D)	1.430 - 1.435
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.