Description

cis-1,3-Cyclohexanedicarboxylic Acid is a versatile alicyclic dicarboxylic acid derivative with a defined stereochemistry, serving as a critical building block in advanced organic synthesis. Its rigid, saturated cyclohexane backbone with two carboxyl groups in the cis configuration makes it a valuable precursor for creating complex molecular architectures with specific spatial orientations. This compound is essential for research and production in the pharmaceutical, agrochemical, and polymer industries, where it is used to synthesize active ingredients, functional monomers, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a rigid, cis-substituted cyclohexane core.
• Polymer Chemistry: Used as a monomer or co-monomer in the production of polyesters, polyamides, and other specialty polymers, imparting rigidity and specific chemical functionality.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced stability and efficacy.
• Ligand and Catalyst Development: The carboxyl groups can be functionalized to create chelating ligands for metal catalysts used in asymmetric synthesis and other catalytic processes.
• Fine Chemical Production: Employed in the manufacture of dyes, flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for probing structure-activity relationships.

Basic Information

Item	Detail
Product Name	cis-1,3-Cyclohexanedicarboxylic Acid
CAS No.	2305-31-9
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	cis-Hexahydroisophthalic Acid; (1R,3S)-1,3-Cyclohexanedicarboxylic Acid; (1S,3R)-1,3-Cyclohexanedicarboxylic Acid; Cyclohexane-1,3-dicarboxylic acid, cis-; 1,3-Cyclohexanedicarboxylic acid, (1R,3S)-rel-; NSC 163944
EINECS	Contact for details

Quality Control

Our cis-1,3-Cyclohexanedicarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay, enantiomeric excess (if applicable), and limits for residual solvents and heavy metals. Our quality commitment ensures reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.