Description

cis-4-Cyclohexene-1,2-Dicarboxylic Acid is a versatile, high-purity organic compound featuring a cyclohexene ring with two carboxylic acid groups in a cis configuration. This specific stereochemistry makes it a valuable chiral building block and intermediate for synthesizing complex molecules. It is essential for research and production in advanced pharmaceutical development and fine chemical manufacturing. Industries requiring high-quality, consistent intermediates for asymmetric synthesis and polymer modification rely on this product.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing cardiovascular and central nervous system drugs.
• Fine Chemical Synthesis: Serves as a precursor for producing specialty chemicals, including complex esters, amides, and anhydrides used in agrochemicals and performance materials.
• Polymer Chemistry: Used as a monomer or co-monomer to introduce rigidity and functionality into polyesters, polyamides, and other engineering plastics.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical reactions.
• Academic and Industrial R&D: A critical reagent in organic chemistry research for studying Diels-Alder reactions and other cycloaddition processes.
• Cosmetic Ingredient Intermediate: Used in the synthesis of certain specialty esters that function as emollients or texture enhancers in high-end formulations.

Basic Information

Product Name	cis-4-Cyclohexene-1,2-Dicarboxylic Acid
CAS No.	2305-26-2
Molecular Formula	C8H10O4
Molecular Weight	170.16 g/mol
Synonyms	cis-1,2,3,6-Tetrahydrophthalic Acid; 4-Cyclohexene-1,2-dicarboxylic acid, (1α,2β,3α,6β)-; δ4-Tetrahydrophthalic Acid; 1,2,3,6-Tetrahydro-cis-benzene-1,2-dicarboxylic Acid; cis-δ4-Tetrahydrophthalic Acid; NSC 8652; (1R,2S,3R,6S)-4-Cyclohexene-1,2-dicarboxylic Acid
EINECS	218-984-8

Quality Control

Our cis-4-Cyclohexene-1,2-Dicarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.