Description

Methyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranoside CAS NO 2296-40-4 is a fully protected derivative of methyl β-D-glucopyranoside, where all hydroxyl groups are silylated with trimethylsilyl (TMS) groups. This compound is a critical intermediate in synthetic organic chemistry, particularly in carbohydrate and nucleoside synthesis, where it provides robust protection against unwanted side reactions. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers for the production of complex bioactive molecules.

Application

• Key Intermediate in Oligosaccharide Synthesis: Serves as a protected glycosyl donor or acceptor for the controlled assembly of complex carbohydrate structures.
• Pharmaceutical Research: Used in the synthesis of glycosylated drugs, prodrugs, and molecular probes where selective deprotection is required.
• Glycoconjugate Chemistry: Essential for creating glycopeptides, glycolipids, and other biologically relevant conjugates.
• Building Block for Specialty Chemicals: Provides a versatile scaffold for developing surfactants, chiral auxiliaries, and advanced materials.
• Analytical Reference Standard: Employed as a high-purity standard in chromatographic analysis (HPLC, GC) for method development and quality control.
• Process Chemistry Development: Facilitates scalable synthetic routes in pilot plants and commercial manufacturing of fine chemicals.

Basic Information

Product Name	Methyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranoside
CAS No.	2296-40-4
Molecular Formula	C19H46O6Si4
Molecular Weight	482.90 g/mol
Synonyms	Methyl 2,3,4,6-Tetra-O-trimethylsilyl-β-D-glucopyranoside; Methyl β-D-Glucopyranoside Tetrakis(trimethylsilyl) Ether; 1-Methoxy-2,3,4,6-tetra-O-(trimethylsilyl)-β-D-glucopyranose; TMS-protected Methyl β-D-Glucoside; Per-O-trimethylsilylated Methyl β-D-Glucoside; Methyl β-D-Glucoside TMS Ether; 2296-40-4; β-D-Glucopyranoside, methyl 2,3,4,6-tetrakis-O-(trimethylsilyl)-
EINECS	Contact for details

Quality Control

Our production of Methyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-β-D-Glucopyranoside adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and process applications. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as assay (by HPLC/GC), identity confirmation (IR, NMR), and purity profile. We support compliance with cGMP and ISO 9001 standards for critical pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC/GC)	≥ 95.0%
Purity (by area normalization)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.