Description

Phenol, 4-Chloro-2,5-Difluoro- is a halogenated phenol derivative serving as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Building block for herbicides, fungicides, and pesticides, where the halogen atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated aromatic cores for electronic display and lighting applications.
• Polymer Modification: Intermediate for introducing halogenated phenolic units into specialty polymers to alter thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic aromatic substitution to introduce functionalized phenolic groups.
• Dye & Pigment Manufacturing: Precursor for synthesizing halogenated dyes with specific color fastness and spectral properties.

Basic Information

Product Name	Phenol, 4-Chloro-2,5-Difluoro-
CAS No.	2268-02-2
Molecular Formula	C6H3ClF2O
Molecular Weight	164.54 g/mol
Synonyms	4-Chloro-2,5-difluorophenol; 2,5-Difluoro-4-chlorophenol; 4-Chloro-2,5-difluoro-1-hydroxybenzene; 1-Chloro-4-fluoro-2-hydroxy-5-fluorobenzene; Phenol, 4-chloro-2,5-difluoro-; 2268-02-2; 4-Cl-2,5-F2-Phenol
EINECS	Contact for details

Quality Control

Our Phenol, 4-Chloro-2,5-Difluoro- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging, or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.