Description

4-Adamantyl-1-Bromobenzene is a high-value brominated aromatic building block featuring a rigid, bulky adamantane moiety. This unique structural combination makes it a critical intermediate for synthesizing advanced materials and pharmaceutical candidates. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the adamantyl group can enhance biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating organic semiconductors and charge-transport materials used in display and lighting technologies.
• Polymer Modification: Acts as a monomer or cross-linking agent to introduce high thermal stability and rigidity into specialty polymers and resins.
• Ligand Synthesis for Catalysis: Employed in the preparation of bulky phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Academic & Industrial Research: A versatile reagent for methodological development in organic synthesis, including cross-coupling reactions like Suzuki-Miyaura and Buchwald-Hartwig amination.

Basic Information

Product Name	4-Adamantyl-1-Bromobenzene
CAS No.	2245-43-4
Molecular Formula	C16H19Br
Molecular Weight	291.23 g/mol
Synonyms	1-Bromo-4-(1-adamantyl)benzene; 1-Bromo-4-adamantylbenzene; 4-(1-Adamantyl)bromobenzene; p-Adamantylbromobenzene; 4-Bromophenyladamantane; (4-Bromophenyl)adamantane; Adamantan-1-yl-4-bromobenzene; 4-(Tricyclo[3.3.1.13,7]decan-1-yl)bromobenzene
EINECS	Contact for details

Quality Control

Every batch of 4-Adamantyl-1-Bromobenzene is produced under a strict quality management system. We provide comprehensive analytical data including HPLC purity (typically ≥97%), identity confirmation by NMR and FT-IR, and residual solvent analysis to meet rigorous R&D and scale-up requirements. A detailed Certificate of Analysis (COA) is supplied with each shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling under subdued light is recommended for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.