Description

(Isopropyl)Methylchlorosilane is a highly reactive organosilicon compound, specifically a chlorosilane, widely used as a key intermediate in organosilicon chemistry. Its primary value lies in its ability to introduce the isopropylmethylsilyl protecting group, offering a strategic balance between steric bulk and reactivity for sensitive synthetic transformations. This makes it an essential reagent for pharmaceutical R&D, agrochemical synthesis, and the production of advanced silicone materials where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block and protecting group reagent in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where silicon-containing moieties can enhance biological activity and stability.
• Silicone Polymer Modification: Acts as a functional monomer or cross-linking agent to tailor the properties of silicone resins, rubbers, and fluids.
• Surface Treatment Agent: Employed in the silylation of inorganic surfaces like silica or glass to impart hydrophobic characteristics.
• Organic Synthesis Reagent: Utilized as a versatile silylating agent for protecting hydroxyl groups in complex organic molecule synthesis.
• Material Science Research: Key precursor in developing novel silicon-based hybrid materials, dendrimers, and nanostructured systems.

Basic Information

Product Name	(Isopropyl)Methylchlorosilane
CAS No.	2227-32-9
Molecular Formula	C4H11ClSi
Molecular Weight	122.67 g/mol
Synonyms	Chloro(isopropyl)methylsilane; Isopropylmethylchlorosilane; Methyl(isopropyl)chlorosilane; (Isopropyl)methylsilyl chloride; 1-Chloro-1-methyl-1-silapropane; Silane, chloromethyl(1-methylethyl)-; NSC 163022
EINECS	218-759-5

Quality Control

Our (Isopropyl)Methylchlorosilane is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Density (at 20°C)	0.88 - 0.92 g/mL
Refractive Index (n20D)	1.410 - 1.420
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.