Description

2-(Hydroxyimino)-Propanoic Acid is an α-oxime carboxylic acid derivative with a reactive oxime functional group and acidic proton, widely employed as a specialty intermediate in fine chemical synthesis. Its structural duality—combining chelating capability, nucleophilic reactivity, and pH-dependent solubility—enables precise control in catalytic and functionalization processes. This compound is essential for manufacturers developing pharmaceutical actives, agrochemicals, metal-chelating agents, and advanced polymer modifiers. The 2-(Hydroxyimino)-Propanoic Acid CAS NO 2211-14-5 is supplied under stringent quality protocols to ensure batch-to-batch consistency and regulatory compliance.

Application

• Key synthetic intermediate in the preparation of β-lactam antibiotics and oxime ether prodrugs
• Chelating ligand for transition-metal catalysts in asymmetric oxidation and C–N coupling reactions
• Building block for photoactive agrochemicals, including herbicidal oxime esters and fungicidal derivatives
• Functional monomer in stimuli-responsive hydrogels and smart coatings (pH- and redox-triggered crosslinking)
• Reagent for selective derivatization of carbonyl compounds in analytical biochemistry workflows
• Stabilizer and co-catalyst in peroxide-initiated polymerizations of acrylic and vinyl monomers

Basic Information

Product Name	2-(Hydroxyimino)-Propanoic Acid
CAS No.	2211-14-5
Molecular Formula	C3H5NO3
Molecular Weight	103.08 g/mol
Synonyms	Acetone oxime carboxylic acid; 2-Hydroxyiminopropanoic acid; α-Hydroxyiminopropionic acid; 2-Oximinopropanoic acid; Hydroxyiminopropionic acid; Propanoic acid, 2-(hydroxyimino)-; 2-(Hydroxyimino)propionic acid; Oximinopropionic acid
EINECS	218-637-9

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches are verified for identity (IR, HPLC), assay (titration), residual solvents (GC), heavy metals (ICP-MS), and impurity profile (HPLC–DAD). The material meets ACS Reagent Grade specifications and is manufactured under ISO 9001-certified quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store under inert atmosphere (nitrogen or argon) at 15–25°C. Due to its easily oxidized nature, avoid exposure to air, moisture, and elevated temperatures. Keep away from strong oxidizing agents and alkaline materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (by titration)	≥ 98.5%
Loss on drying	≤ 0.5%
Residue on ignition	≤ 0.1%
Heavy metals (as Pb)	≤ 10 ppm
Related substances (HPLC)	Single impurity ≤ 0.3%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.