Description

4-Methylphenyl Trifluoromethyl Sulphoxide is a specialized organosulfur compound featuring a trifluoromethylsulfinyl group attached to a toluene ring. This unique structure makes it a valuable building block and intermediate in advanced synthetic chemistry, particularly where the introduction of fluorine-containing motifs is required. It is primarily utilized by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, especially in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral sulfoxide ligands used in asymmetric catalysis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals with unique electronic or optical properties.
• Organic Synthesis Building Block: A versatile reagent for introducing the -S(O)CF3 moiety into complex molecular architectures.
• Fluorine Chemistry Studies: Used in academic and industrial R&D to study the effects of fluorinated sulfoxides on molecular reactivity and physical properties.

Basic Information

Product Name	4-Methylphenyl Trifluoromethyl Sulphoxide
CAS No.	2189-43-7
Molecular Formula	C8H7F3OS
Molecular Weight	208.20 g/mol
Synonyms	1-Methyl-4-(trifluoromethylsulfinyl)benzene; p-Tolyl Trifluoromethyl Sulfoxide; α,α,α-Trifluoro-p-tolyl Sulfoxide; (4-Methylphenyl)(trifluoromethyl)sulfoxide; 4-(Trifluoromethylsulfinyl)toluene; Trifluoromethyl p-tolyl sulfoxide
EINECS	Contact for details

Quality Control

Our 4-Methylphenyl Trifluoromethyl Sulphoxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.