Description

5-Chloroisophthalic Acid is a high-purity aromatic dicarboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of the chlorine substituent, which enables precise functionalization and modification of polymer backbones and pharmaceutical intermediates. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a functionalized isophthalic acid core.
• Polymer Chemistry: Monomer for producing modified polyesters, polyamides, and liquid crystal polymers (LCPs) with enhanced thermal stability and mechanical properties.
• Agrochemical Synthesis: Building block for manufacturing herbicides, fungicides, and plant growth regulators.
• Metal-Organic Frameworks (MOFs): Organic linker used in the construction of porous coordination polymers for gas storage, separation, and catalysis.
• Dye and Pigment Manufacturing: Intermediate for creating complex organic colorants and photographic chemicals.
• Cross-linking Agent: Used in epoxy resin systems and coatings to improve hardness and chemical resistance.
• Laboratory Research: Versatile reagent in academic and industrial R&D for exploring new synthetic pathways and material properties.

Basic Information

Product Name	5-Chloroisophthalic Acid
CAS No.	2157-39-3
Molecular Formula	C8H5ClO4
Molecular Weight	200.57 g/mol
Synonyms	5-Chloro-1,3-benzenedicarboxylic Acid; 5-Chlorobenzene-1,3-dicarboxylic Acid; Isophthalic Acid, 5-Chloro-; 3-Carboxy-5-chlorobenzoic Acid; 5-Chloroisophthalate; 2157-39-3; 5-Cl-IPA
EINECS	218-476-9

Quality Control

Our 5-Chloroisophthalic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for purity and consistency. Certificates of Analysis (COA) detailing results for assay, related substances, and residual solvents are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards as required for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Sparingly soluble in water; soluble in alkaline solutions and polar organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.