Description

3,4-Dihydro-2H-Pyrrole-5-Carboxylic Acid CAS NO 2139-03-9 is a versatile heterocyclic building block, a pyrroline derivative with a carboxylic acid functional group. This compound is valued for its role as a key synthetic intermediate in the production of complex organic molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, particularly those containing pyrrolidine or proline-like scaffolds, which are common in bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the heterocyclic core can contribute to specific biological activity.
• Fine Chemical Production: Serves as a specialized building block for creating complex flavors, fragrances, and advanced organic materials.
• Academic & Industrial Research: Employed in medicinal chemistry and organic synthesis research for method development and exploring new chemical spaces.
• Peptidomimetic Development: The structure is useful for creating peptide analogs and mimetics in drug discovery programs.

Basic Information

Product Name	3,4-Dihydro-2H-Pyrrole-5-Carboxylic Acid
CAS No.	2139-03-9
Molecular Formula	C5H7NO2
Molecular Weight	113.11 g/mol
Synonyms	2,3-Dihydro-1H-pyrrole-5-carboxylic acid; 3-Pyrroline-5-carboxylic acid; 1,2-Dihydropyrrole-5-carboxylic acid; δ3-Pyrroline-5-carboxylic acid; 5-Carboxy-3-pyrroline; 3,4-Dihydro-2H-pyrrole-5-carboxylic acid; 3,4-Dihydro-2H-pyrrol-5-carboxylic acid
EINECS	218-376-7

Quality Control

Our 3,4-Dihydro-2H-Pyrrole-5-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.