Description

1,4-Bis((Trimethylsilyl)Oxy)Benzene is a high-purity organosilicon compound, widely recognized as a versatile silylating agent and a key protected intermediate in advanced organic synthesis. Its primary value lies in its ability to introduce the robust trimethylsilyl (TMS) protecting group onto phenolic hydroxyls, enhancing the stability and solubility of sensitive molecules during complex chemical transformations. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used as a key building block and protecting group reagent in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Serves as a crucial intermediate in the production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials where phenolic protection is required.
• Organic Synthesis Reagent: Functions as a versatile silylating agent in laboratory and industrial-scale reactions to protect phenolic -OH groups from unwanted reactions.
• Chemical Research: A valuable tool for academic and industrial R&D in developing new synthetic methodologies and novel organic compounds.

Basic Information

Product Name	1,4-Bis((Trimethylsilyl)Oxy)Benzene
CAS No.	2117-24-0
Molecular Formula	C12H22O2Si2
Molecular Weight	254.48 g/mol
Synonyms	1,4-Bis(trimethylsiloxy)benzene; Hydroquinone bis(trimethylsilyl) ether; 1,4-Bis(trimethylsilyloxy)benzene; Hydroquinone O,O'-bis(trimethylsilyl); Bis(trimethylsilyl) hydroquinone ether; TMS-hydroquinone; 2,5-Bis(trimethylsiloxy)-1,4-cyclohexadiene; p-Bis(trimethylsiloxy)benzene
EINECS	218-322-1

Quality Control

Our 1,4-Bis((Trimethylsilyl)Oxy)Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and physical characteristics to meet the stringent requirements of our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can compromise product quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.