Description

2-Chloro-1,4-Dimethoxybenzene is a versatile halogenated aromatic ether, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its dual functional groups—the chloro and methoxy substituents—which enable selective electrophilic substitution and coupling reactions, making it a key building block for complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with complex aromatic backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its chlorinated dimethoxybenzene structure is incorporated.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic electronic materials and liquid crystal compounds.
• Dye & Pigment Intermediate: Employed in the manufacture of specialized dyes and organic pigments, leveraging its aromatic reactivity.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers and high-performance resins.
• Organic Synthesis & Research: A valuable reagent in academic and industrial laboratories for constructing complex molecular architectures via cross-coupling and functional group transformations.

Basic Information

Product Name	2-Chloro-1,4-Dimethoxybenzene
CAS No.	2100-42-7
Molecular Formula	C8H9ClO2
Molecular Weight	172.61 g/mol
Synonyms	1-Chloro-2,5-dimethoxybenzene; 2,5-Dimethoxychlorobenzene; 2-Chlorohydroquinone dimethyl ether; Chlorohydroquinone dimethyl ether; 2-Chloro-1,4-dimethoxy-benzene; 2-Chlorodimethoxybenzene; 2,5-Dimethoxy-1-chlorobenzene; 2-Chlorohydroquinone dimethyl ether
EINECS	218-263-6

Quality Control

Our 2-Chloro-1,4-Dimethoxybenzene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	55 - 58 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.