Description

2-Chloro-6-Fluorophenol is a versatile halogenated phenol derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and pesticides, where the phenol core provides a reactive site for further functionalization.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or modifying agent in the production of specialty polymers and liquid crystal materials for electronic displays.
• Dyestuff & Pigment Manufacturing: Serves as an intermediate for synthesizing complex dyes and organic pigments.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and material properties.
• Cross-Coupling Reactions: Useful in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination for constructing biaryl structures.

Basic Information

Product Name	2-Chloro-6-Fluorophenol
CAS No.	2040-90-6
Molecular Formula	C6H4ClFO
Molecular Weight	146.55 g/mol
Synonyms	2-Chloro-6-fluorophenol; 6-Fluoro-2-chlorophenol; o-Chloro-o-fluorophenol; 1-Chloro-3-fluoro-2-hydroxybenzene; Phenol, 2-chloro-6-fluoro-; 2-Hydroxy-3-chlorofluorobenzene; 2-Fluoro-6-chlorophenol
EINECS	218-041-5

Quality Control

Our 2-Chloro-6-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	32 - 36 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.